Garcinia cambogia is hot. Nearly one million Americans on a monthly basis Google this supposed weight-loss supplement. They’re seeking reviews on garcinia cambogia’s effectiveness, what type of side effects it causes, and where they could purchase it. My mother recently got a new bottle of the pills at Costco because she saw a segment about buy pure garcinia cambogia on a Tv program.

Manufacturers declare that garcinia cambogia boosts weight loss by, amongst other things, “slowing the body’s capability to absorb fat,” “replacing fat with toned muscles,” and even increasing your mood and suppressing “the drive to react to stressful situations with food.” How, you may ask? It’s mostly pinned on hydroxycitric acid (HCA), a substance present in garcinia cambogia that seems to inhibit an enzyme called citrate lyase and interferes with fatty acid metabolism.

“HCA does accomplish that-however in a petri dish,” says Steven Heymsfield, M.D., the former head of your Pennington Biomedical Research Center in Baton Rouge, La. “Converting that to actual fat loss in humans would take 1,000 steps beyond that,” he says.

Way back in 1998, Heymsfield published the very first randomized controlled trial on the effectiveness of garcinia cambogia, in the Journal from the American Medical Association. He found no weight-loss benefits. Heymsfield, who consistently study the topic of weight-loss supplements at Pennington, states that in regards to a dozen negative studies have since been published about garcinia cambogia. But which has not stopped marketers from the supplement, he says, from “weaving a story with obscure facts. Maybe each fragment has some validity, but when you wind it together this makes no sense whatsoever.”

His original study, conducted by Columbia University’s Obesity Research Center, considered 135 overweight men and women age 18 to 65; about half received garcinia cambogia as well as the other half a placebo 3 x every day before meals. Both groups ate an increased-fiber diet and returned for evaluation every fourteen days. At the conclusion of the 12-week trial, there were no important variations in weight reduction between the two groups.

Overview of 12 trials involving forskolin fat burner published from the Journal of Obesity in the year 2011 got to the same conclusion. Another study by researchers at Victoria University in Melbourne, Australia, and published in 2013 inside the journal Complementary Therapies in Medicine found that overall the evidence for garcinia cambogia was “not compelling.”

Regarding garcinia cambogia’s unwanted effects, controlled studies and animal research has found only a few, although Heymsfield says, “I don’t think it’s totally safe.”

During 2009 the meals and Drug Administration warned consumers about Hydroxycut, a product or service line containing garcinia cambogia and plenty of other ingredients, based on serious reports of medical problems, including jaundice, elevated liver enzymes, liver damage requiring a transplant, and something death from liver failure. The FDA stated it be11yfat unable to determine exactly which ingredients were of the liver injuries. (Hydroxycut’s manufacturer, Iovate Health Sciences, withdrew these products, while it has since returned a reformulated product for the market containing no garcinia cambogia.)

“Being obese is actually difficult because only some of it is related to self-control,” Heymsfield says. “And it’s not easy to lose weight inside our environment. Just preventing further an increase in weight is definitely an accomplishment for some people.” The biggest problem with benefits of forskolin, Heymsfield says, besides being a complete waste of money, is that it distracts people from paying attention to the main things in relation to weight reduction: upping your activity level and eating a healthier diet.